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Study population Adult patients (18 years) with T2DM and ESRD who were prescribed a GLP-1 RA between January 1, 2016, and July 17, 2025, were eligible for inclusion

The continuous hyperglycemia can induce target organ damage (TOD) by increasing the risk of panvascular disease, including microvascular disease (such as diabetic retinopathy, nephropathy and neuropathy), and atherosclerotic macrovascular disease (cardiovascular, cerebrovascular, and other peripheral vascular diseases)